The Optimal Creatine Protocol for Strength, Brain, and Longevity | Darren Candow, PhD
He recommends higher doses (5-10g daily) to support aging tissues like bone and brain, particularly under metabolic stress, and debunks common myths regarding kidney damage, hair loss, and dehydration.summaryBrain Health & Stress: The brain is resistant to creatine uptake due to the blood-brain barrier. High doses (20g/day) or prolonged supplementation are needed to increase brain creatine stores, which show benefits during takeawayDosing Strategies: A loading phase (20g/day for 7 days) is only necessary for rapid muscle saturation. For general health (bone/brain), a daily dose of 5-10g is sufficient. For specific stressors (sleep deprivation), acutakeaway














