Dr. Steve Horvath on epigenetic aging to predict healthspan: the DNA PhenoAge and GrimAge clocks

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Chapters & Sections (54)

0:00 Introduction to Horvath Aging Clock chapter 3
0:00 Introduction to Horvath Aging Clock
1:48 Biological Age vs Chronologic Age
3:00 Biological Age vs Chronological Age
5:16 Epigenetic Aging Rates and Hispanic Ancestry chapter 3
5:16 Epigenetic Aging Rates and Hispanic Ancestry
7:41 Epigenetic Aging and Lifestyle Interventions
9:03 Epigenetic Clock and Aging Consistency
10:21 Stability of Epigenetic Clocks in Aging chapter 3
10:21 Stability of Epigenetic Clocks in Aging
11:48 DNA Damage in Blood at Room Temperature
13:03 Epigenetic Clocks and Methylation Patterns
14:41 Predicting Biological Age and Lifespan chapter 4
14:41 Predicting Biological Age and Lifespan
16:19 Anti-Aging Interventions and Epigenetic Clocks
17:47 Predictive Value of Epigenetic Age Biomarkers
19:33 Cancer and Epigenetic Age Acceleration
21:25 Immune System Role in Parkinson's Disease chapter 2
21:25 Parkinson's Disease and Immune System Connection
23:45 Telomere Length and Aging Predictions
26:02 Telomere Length and Lifestyle Factors chapter 2
26:02 Telomere Length and Lifestyle Factors
28:12 Epigenetic Clock and Lifestyle Effects
30:40 Importance of Measuring Tissue Types for Aging chapter 2
30:40 Importance of Tissue-Specific Aging Mechanisms
32:50 Hematopoietic Stem Cell Transplantation and Aging
35:25 Parabiosis and Epigenetic Clocks in Mice chapter 1
35:25 Parabiosis and Epigenetic Clocks in Mice
39:38 Epigenetic Clock and Aging Mechanisms chapter 3
39:38 Epigenetic Regulation of Cell Cycle Progression
41:36 Epigenetic Age and DNA Methyl Transfer Enzymes
43:10 Epigenetic Clockwork Regulation and Aging
45:17 Epigenetic Age and Cellular Differentiation chapter 3
45:17 Cellular Aging and Epigenetic Changes
46:42 Cellular Aging and Epigenetic Clock Reset
48:15 Gene Manipulation and Cellular Rejuvenation
49:31 Epigenetic Clock and Aging Intervention chapter 2
49:31 Epigenetic Clock and Aging Intervention
52:02 Effects of Caloric Restriction on Epigenetic Aging
54:20 Discussion on Aging and Fasting Studies chapter 3
54:20 Discussion on Fasting Study and Human Data
55:58 Intermittent Fasting and Epigenetic Aging
57:14 Vitamin D and Epigenetic Clock Reduction
58:53 Discussing Potential Interventions for Aging chapter 3
58:53 Exploring Interventions for Aging and Health
1:00:41 Benefits of Surrogate Markers in Clinical Trials
1:02:05 Aging Process and Sleep Quality Association
1:03:35 Epigenetic Aging and Anti-Aging Interventions chapter 6
1:03:35 Aging and Epigenetic Clock Validation
1:05:25 Senolytics and Epigenetic Aging Relationship
1:07:09 Epigenetic Clocks and Aging Process
1:08:46 Epigenetic Clocks and Methylation Patterns
1:09:57 Epigenetics and Aging Research Insights
1:11:25 Discussion on Research and Learning Resources

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