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Chapters & Sections (103)
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0:08
Defining Assemblids and Organoids
1:03
Assemblid Concept and Brain Organization
2:07
Potential Applications of Assemblids
3:39
Defining Organoids and Their Purpose
4:12
Organoid Function and Modeling
5:18
Stem Cell Research and Breakthroughs
6:51
Stem Cell Properties and Developmental Restrictions
7:55
Cell Reprogramming Experiment and Gene Expression
8:58
Autism Research Challenges and Stem Cell Potential
10:00
Initial Challenges in Stem Cell Research and Disease Modeling
10:31
Focusing on a Specific Disease for Calibration
11:02
The Need for 3D Cultures and Organoids in Stem Cell Research
11:33
Self-Organization in Biology and the Role of Cells' Instructions
13:09
The Brain's Unique Cell Types and Regions
13:40
Interacting Cells and Assemblids
14:10
Brain's Ability to Reorganize and Self-Organize
15:12
Long-Term Cultivation of Brain Cells
15:44
Maintaining Stem Cells in Culture
16:15
Fascinating Discovery of Timekeeping Ability
17:50
Understanding the Mechanism of Timekeeping
18:52
Cell Culture Media and Measuring Cell Function
19:54
Identifying Neuron Types by Gene Expression and Morphology
20:46
Cell Movement in the Brain
21:27
Assemblid and Guiding Cell Assembly
21:58
Cellular Development and Migration
22:28
Forced Cell Movement and Assembly
23:31
Challenges in Adult Brain Repair
24:02
Potential for Prenatal Intervention and Developmental Plasticity
25:05
Timothy Syndrome and Reverse Engineering
25:35
Modeling Complex Diseases like Autism and Epilepsy
26:07
Single Letter Mutation in Calcium Channel Protein
26:37
Monitoring Calcium Inside Cells and Modeling Disease
27:08
DNA Sequencing and CRISPR Technology Limitations
28:12
Identifying a Solution to Gene Processing
28:42
Understanding the Complexity of Disease
29:12
Empirical Evidence and Human Stem Cell Models
30:15
Animal Model Limitations and Transplantation Methods
30:47
Testing Therapeutics in a Living Organism
31:18
Reconstructing Circuits and Disorders of Software
32:19
Building a Circuit with an Output
32:50
Reconstructing the Cortical Spinal Pathway
34:26
Correcting Mutations Before Birth and Personalized Medicine
34:56
Modeling Diseases with Assemblides and Drug Development
35:29
Understanding Cellular Behavior and the Role of Molecular Biology
36:32
Access to the Brain and Breakthroughs in Psychiatry and Neurology
37:34
Understanding Pain Sensitivity and Nerve Function
38:36
Reconstructing the Pain Pathway
39:37
Synchronizing Neurons and Circuit Function
40:39
Pain Sensitivity in Patients and Cells
41:12
The Brain's Role in Pain Perception
42:46
Mind Over Matter and Pain Pathways
43:47
Distinguishing Pain from Emotional Component
44:48
Reverse Engineering Opioids for Non-Addictive Pain Relief
45:20
The Limitations of Current Opioid Treatment and the Need for a New Approach
45:52
Personal Experience with Pain and Perspective on Athletes' Relationship with Pain
46:54
Empowering Psychiatric Research through Avatar Building and Clue Finding
47:26
Complex Behavior and Hallucination in the Brain
47:57
The Rosetta Stone Analogy and Translation of Complex Phenomena
48:28
Molecular Biology and Reversing Complex Brain Processes
49:00
Clinical Trials and the Future of Human Neuroscience
50:02
Addressing Timothy Syndrome and Other Diseases
50:32
Training and Collaboration in Research Methods
51:02
Global Implementation of Research Methods and Therapeutic Breakthroughs
51:33
Limitations and Complexity in Assemblid Research
53:04
Incomplete Models and the Need for Context
53:35
Video Game and Regulatory Concerns
54:06
Ethical Considerations in Cell Use
55:07
Regulation and Complex Features
56:09
Historical Context of Gene Editing and Ethical Discussions
56:39
The Burden of Psychiatric Disorders and the Potential for Gene Editing
57:10
Neurodiversity and the Spectrum of Autism
57:40
Judging Needs for Repair vs. Acceptance in Neurodiversity
58:42
The Devastating Forms of Autism and the Need for Treatment
59:43
The Importance of Neurological Differences in Neuroscience and Destiny
1:00:45
The Role of Stochastic Forces in Development and Evolution
1:01:47
The Devastating Effects of Certain Conditions and the Human-centric View
1:02:50
The Connection Between Neuroscience and Human Progress
1:03:54
The Importance of Precision in Neuroscience Research