Dr. Paul Saladino

Tetragrammaton with Rick Rubin
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Chapters & Sections (221)

0:15 Background and Career Choice chapter 4
0:30 Physician Assistant School and Early Career
1:00 Influence of Family Member's Work-Life Balance
2:02 Personal Break and Rediscovery
2:32 Realization of PA Practice Limitations
3:33 Critique of Western Medicine chapter 5
3:33 Siloing in Medicine and Holistic Systems
4:07 Broken Heart Syndrome and Emotional Connection
4:38 Questioning Mainstream Medicine and Root Cause Thinking
5:09 Fascination with Functional Medicine and Root Cause Ideas
6:11 Rebellion Against the Broken Core Narrative
6:42 The Importance of Diet in Health chapter 1
6:42 Diet's Impact on Health and Pharmaceuticals
7:13 Personal Experience with Raw Veganism chapter 3
7:13 Introduction to Raw Veganism
8:16 Challenges with Raw Vegan Diet
9:19 Negative Physical and Social Consequences
10:21 The Influence of Paleo and Functional Medicine on Personal Health chapter 4
10:21 The Concept of Paleo and DNA-Driven Nutrition
10:54 Personal Experience with Paleo and Evolutionary Signals
11:25 Adding Meat to the Diet and Initial Results
12:27 Food Triggers and Allergies vs. Anaphylaxis
13:28 Autoimmune Conditions and Immune System Reaction chapter 3
13:28 Autoimmune Conditions in Skin, Brain, and Other Organs
14:29 Gut-Immune System Connection in Autoimmune Diseases
14:59 Potential Immune System Triggers and Neuroinflammation
16:05 Squarespace Website Building and Analytics chapter
17:06 Understanding Individual Food Reactions chapter 4
17:06 Complexity of Immune System Programming and Personal Differences
17:37 Personal Experience with Food Reactions and Overmedication
18:08 The Importance of Personal Discovery and Metrics for Identifying Triggers
18:39 Common Food Triggers and the Role of Plant Foods
20:10 Introduction to the Carnivore Diet chapter 5
20:10 Michaela Peterson's Experience with the Carnivore Diet
20:42 Jordan Peterson's Discussion of Autoimmune Conditions
21:12 Fascination with the Carnivore Diet as an Experiment
21:43 The Importance of Signal vs Noise in Diets and Environments
22:13 Elimination Diet and the Carnivore Diet as a Simplification Experiment
26:19 Discussion on Honey and Local Food chapter 3
26:19 The Importance of Local Honey and Bees
26:49 Comparison of Imported vs. Local Food in Costa Rica
27:52 Personal Experience with Carnivore Diet and Health Issues
29:28 Electrolyte Deficiency and Mitochondrial Function chapter 5
29:28 Testosterone Decline and Electrolyte Deficiency
29:58 Ketogenic Diet and Insulin Levels
30:29 Mitochondrial Function and Alternative Therapies
31:00 Electrolyte Issues with Ketogenic Diet
32:00 Personal Experience with Electrolyte Deficiency
33:02 Personal Experience with Diet and Health chapter 5
33:02 Adding Plant-Based Foods to Diet and Realizations
33:33 Debunking Carbohydrate Myths in the Keto Community
34:04 Insulin Resistance and Macronutrients
35:07 Electrolytes for Hydration and Energy
36:09 Keto vs Carnivore Diets
36:39 Ketosis, Glucogenesis, and Fat-Based Metabolism chapter 2
36:39 Glucogenesis and Ketosis in the Body
37:12 Ketone Production and Mitochondrial Function
39:18 Raw Dairy vs Pasteurized Dairy chapter 1
39:18 Raw Dairy and Evolutionary History
39:50 The Terrain Hypothesis and Microbial Balance chapter 3
39:50 The Terrain Hypothesis and its Relevance to Disease
40:21 MRSA and the Misconception of Superbugs
40:52 The Importance of Commensal Bacteria and Gut Health
42:56 Raw Milk Benefits and Risks chapter 5
42:56 Unique benefits of unpasteurized milk and potential effects on immune system
43:27 Raw milk consumption and reduced risk of asthma, eczema, and allergies
43:58 Raw milk controversy and potential negative effects on immune system
44:29 Comparison of raw milk risks to other foodborne illnesses
45:00 Raw milk safety and potential benefits, including unique oligologic benefits
46:02 Raw Milk, Lactose Intolerance, and Fermentation chapter 3
46:02 Raw Milk and Lactose Intolerance
47:05 Fermentation and Digestibility
48:07 Fermented Foods and Detoxification
49:09 Plant Defense Chemicals and Seed Vulnerability chapter 5
49:09 Grains and Seeds as Colloquial Terms
49:41 Seed Defense Chemicals and Evolutionary Warfare
50:41 Digestive Enzyme Inhibitors and Defense Chemicals in Seeds
51:14 Cyanide Derivatives, Gluten, and Seed Immunogenicity
51:45 Seed Digestibility and Gut Health
52:16 Phytic Acid and Gluten Issues in Grains chapter 2
52:16 Phytic Acid in Oats and Wheat
52:47 Impact of Sourdough Fermentation on Grains
55:55 The Problem with Factory Farming and Grain Feeding chapter 3
55:55 Grain Feeding and Contamination of Cattle Feed
56:27 Health Issues in Grain-Fed Cattle
56:58 Grass-Fed vs. Grain-Finished Meat and Greenwashing
57:29 Calcium and Phosphorus Balance in Diet chapter 1
57:29 Finding Trustworthy Producers of Grass-Fed and Grass-Finished Meat
59:01 The Importance of Grass-Fed Meat and Raw Milk chapter
1:00:04 Incorporating Calcium-Rich Foods into the Carnivore Diet chapter
1:02:08 Plant Defense Mechanisms chapter 4
1:02:08 Communication between Plants and Animals/Humans
1:02:39 Plant-Fruit Interactions and Defense Chemicals
1:03:09 Fermentation and Plant Defense
1:03:40 Sugar Content in Fruit and its Effects on Humans
1:05:12 Endothelial Dysfunction and Blood Sugar chapter 5
1:05:12 Inducing Endothelial Dysfunction with Glucose
1:05:43 Improving Glucose Tolerance and Endothelial Function with Fruit Juice
1:06:13 Fruit Juice and Its Effects on Endothelial Function and Oxidation
1:06:46 Comparison of Fruit Juice to Pure Sugar and High Fructose Corn Syrup
1:07:48 Fructose as a Carbohydrate and Its Effects on the Body
1:08:19 Fructose in Isolation vs. Natural Context chapter 4
1:08:19 Fructose in Ketosis and Isolation
1:08:49 Reductionism in Nutrition Research
1:09:22 Bacterial Overgrowth and Endotoxin
1:09:53 Complexity of Fruit vs. Isolated Compounds
1:11:28 Honey as a Food Source and its Health Benefits chapter 4
1:11:28 Honey as a Food Source in Hza Culture
1:12:00 Honey's Calorie Density and Health Benefits
1:12:30 Insulin Sensitivity and Honey's Effects on Diabetes
1:13:33 Misconceptions about Blood Sugar and Insulin Resistance
1:14:34 Fruit and Honey, Insulin Resistance, and Metabolic Health chapter 4
1:14:34 Fruit and Honey in Metabolically Healthy Individuals
1:15:04 Insulin Resistance and Polyunsaturated Fatty Acids
1:16:07 Methodological Issues in Seed Oil Studies
1:17:42 Oxidation and Peroxidation of Lipids
1:18:14 Seed Oil Processing and Oxidation chapter 4
1:18:14 Mechanisms to Counteract Liability in Whole Foods vs Seed Oils
1:18:44 Damage Caused by Oil Processing and Oxidation
1:19:15 Mitochondrial Dysfunction and Cellular Damage from Seed Oils
1:20:16 Need for Further Research and Evolutionary Inappropriateness of Seed Oils
1:21:18 The Problem with Seed Oils chapter 4
1:21:18 Vitamin E Deficiency and Seed Oil Consumption
1:21:49 The History of Seed Oils and the American Heart Association
1:22:20 Saturated Fats and Seed Oils
1:23:55 Ferroptosis and the Effects of Polyunsaturated Fats
1:24:27 Ferroptosis, Oxidation, and Human Health chapter 5
1:24:27 Ferroptosis and Lipid-Induced Cell Death
1:24:57 Oxidation and Electron Movement in the Human Body
1:25:27 Limitations of Mainstream Dietary Recommendations
1:25:58 Correlation Between Red Meat Consumption and Health Outcomes
1:27:00 Sovereignty and Personal Choice in Diet and Lifestyle
1:27:31 Discussion on Plant and Animal Nutrition chapter 3
1:27:31 Associations between Vegetable Consumption and Health Behaviors
1:28:03 Egg Nutrition and Cholesterol
1:28:34 Cholesterol and LDL in the Human Body
1:29:05 Egg Production and Nutrition chapter 1
1:29:05 Egg Health Benefits and Nutrient Complementarity
1:32:09 Egg Allergies and Immune System chapter
1:32:39 Bitter Foods and Plant Communication chapter
1:33:40 Spicy Foods and Gut Irritation chapter
1:34:10 Fiber and Gut Health chapter 5
1:34:10 Fiber's Potential Impact on Gut Lining and Irritation
1:34:45 Fiber as a Panacea for Chronic Health Issues
1:35:16 Short-Chain Fatty Acids and Gut Health
1:35:46 Fiber's Impact on Microbial Diversity and Gut Health Outcomes
1:36:16 Fermented Foods and Gut Health Outcomes
1:37:19 Autoimmune Infiltration and Gut Health chapter 4
1:37:19 Lymphocytic Infiltration and Diverticulosis
1:37:49 Fiber and Gut Health Association
1:38:21 Hypotheses on Fiber and Immune Reactions
1:39:54 Coffee and Gut Health Concerns
1:40:25 Caffeine and Sleep Quality chapter 5
1:40:25 Caffeine's Impact on Sleep Architecture
1:40:56 Caffeine Persistence and Sleep Disruption
1:41:28 Personal Experience with Coffee and Sleep Quality
1:41:59 Elimination Diets and Simplification for Health Issues
1:42:30 Plant Defense Chemicals in Vegetables and Health
1:43:33 Oxalates in Certain Foods chapter 3
1:43:33 Oxalates in Spinach and Other Foods
1:44:04 Turmeric and Oxalates
1:45:07 Potential Misconceptions about Turmeric and Inflammation
1:46:39 MTHFR Gene and Folate Conversion chapter 5
1:46:39 MTHFR Gene and Folate Conversion Basics
1:47:13 Consequences of Not Making Enough Methylfolate
1:47:42 MTHFR Genetic Testing and Homosysteine Levels
1:48:46 Methylfolate Supplement and B Complex
1:49:18 Creatine Supplement and Benefits
1:49:48 Dietary Choices and Supplements chapter 5
1:49:48 Reducing Red Meat Consumption and Supplementing with Creatine
1:50:20 Protein Intake and Recommendations
1:50:52 Animal-Based Diet and Plant Foods
1:51:23 Bioavailability of Protein from Animal and Plant Sources
1:52:26 Collagen Protein and Other Supplements
1:52:58 The Importance of Collagen and Tendons in Meat chapter 4
1:52:58 Collagen and Tendon Content in Steakhouse Meat
1:53:29 Balancing Collagen and Other Nutrients in Meat
1:54:01 Hydrolyzed Beef Protein and Collagen Powder
1:54:31 Comparison of Whey, Beef, and Egg Protein Powders
1:56:04 Discussion on Food and Nutrition chapter 4
1:56:04 Egg Production and Coloration
1:56:34 Soybeans as a Protein Source
1:57:05 Potential Health Risks of Soy Consumption
1:58:08 Hunter-Gatherer Diet and Food Preferences
1:59:08 Food Preferences in African Culture chapter 2
1:59:08 Food Preferences in African Culture
1:59:39 Perspective on Vegetables as Medicine
2:00:05 Vegetables as Food and Medicine chapter 3
2:00:05 Contrast between Healthy and Fat Loss Diets
2:00:42 OIC as a Pharmaceutical Solution
2:01:45 Criticizing the Need for OIC
2:02:16 Critique of Western Medicine and Obesity chapter 3
2:02:16 Pharmaceutical Industry Influence and Genetic Obesity
2:02:49 Lifestyle-Based Obesity and Food Quality
2:03:20 Food Quality and Satiety, Calorie Restriction
2:05:26 Processed Meats and Additives chapter 4
2:05:26 Unhealthy Meat Options and Microplastics
2:05:59 Healthier Meat Options and Grass-Fed
2:06:30 Raw Dairy and Butter Options
2:07:00 Vitamin K2 in Cheese and Cardiovascular Health
2:08:03 Dairy and Vitamin K2 chapter 1
2:08:03 Fruits, Vegetables, and Grains
2:08:35 The Problem with Unprocessed Plant Foods chapter 4
2:08:35 Phytic Acid in Oats and Mineral Deficiencies
2:09:05 Grains as a Problematic Food Group
2:09:36 Ultra-Processed Foods and Health Risks
2:11:11 Comparison of Carnivore and Western A Price Diets
2:11:42 Impact of Modern Diet on Human Health chapter 3
2:11:42 Dental and Facial Structure Changes due to Processed Foods
2:12:14 Weston A Price's Observations on Traditional Diets and Health
2:12:46 Fasting and Intermittent Fasting: Potential Risks and Limitations
2:14:52 Autophagy and Fasting chapter 5
2:14:52 Cortisol and Intermittent Fasting
2:15:24 Autophagy and Cellular House Cleaning
2:15:54 Potential Problems with Fasting Theory
2:16:25 Fasting and Cellular Damage
2:17:28 Caloric Restriction in Animal Studies
2:17:59 Caloric restriction and membrane saturation chapter 3
2:17:59 Seed oils, polyunsaturated fats, and membrane saturation
2:18:30 Intermittent fasting, caloric restriction, and potential side effects
2:19:01 Thyroid hormone and testosterone supplementation

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